Project Lead – Marian McKenzie Plant and Food, Massey
Objective – Kukoamines are found in potatoes and previous research has suggested that these compounds are anti-hypertensive (i.e. can reduce high blood pressure) in mammals. This was identified as a prospective target for the potato industry, following their interest in extraction/utilisation of valuable molecules from potatoes. The earliest paper in which this was reported provides no methods or data so PFR’s aim was to confirm the bioactivity of these compounds.
Update – A trial in which hypertensive rats were fed synthetic kukoamine has provided no evidence to support the claim that these compounds are anti-hypertensive; these results will be published and this line of enquiry will not be pursued further.